RISK STRATIFICATION, REGISTERS AND PROGNOSTIC SCALES IN ACUTE CORONARY SYNDROME

Abstract

Abstract. Aim. The aim of the research is to consider the possibilities most often used in practical cardiology of registers and prognostic scales in acute coronary syndrome (ACS). Discussion. The heterogeneity of the clinical picture, the results of ECG studies, levels of cardiomarkers and pathophysiological mechanisms of ACS cause different levels of risk of cardiac complications and death of patients in the short and long term. In such patients, stratification of risk, especially of early cardiac complications, is a key factor in determining treatment strategies and quality of life. The main method that allows solving these problems is cohort observational programs or registers of different levels and purposes. The GRACE scale is perhaps the most powerful in its predictive value. Unlike other scales, GRACE includes an evaluation of renal function and with the sufficient frequency of renal arterial hypertension associated with ACS and renal impairment (creatinine clearance less than 75 mL / min) the GRACE predictive accuracy improves significantly. Conclusion. Analysis of the literature shows that at present leading centers of cardiology, a lot of attention is given to the development of ACS registers and prognostic scales with maximum power and specificity as well as sufficient ease of use and the possibility of further improvement. The reliability and informativeness of registers and prognostic scales is based on the use of the principles of evidence-based medicine and advanced methods of medical statistics.