<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ecodag</journal-id><journal-title-group><journal-title xml:lang="ru">Юг России: экология, развитие</journal-title><trans-title-group xml:lang="en"><trans-title>South of Russia: ecology, development</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1992-1098</issn><issn pub-type="epub">2413-0958</issn><publisher><publisher-name>State Institute of Applied Ecology of the Republic of Dagestan</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18470/1992-1098-2017-1-107-127</article-id><article-id custom-type="elpub" pub-id-type="custom">ecodag-907</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>МЕДИЦИНСКАЯ ЭКОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>MEDICAL ECOLOGY</subject></subj-group></article-categories><title-group><article-title>ВНУТРИРЕГИОНАЛЬНАЯ ВАРИАБЕЛЬНОСТЬ СЕЛЕНОВОГО СТАТУСА НАСЕЛЕНИЯ</article-title><trans-title-group xml:lang="en"><trans-title>INTERIGIONAL VARIABILITY OF THE HUMAN SELENIUM STATUS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Голубкина</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Golubkina</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор сельскохозяйственных наук, главный научный сотрудник,</p><p>Московская обл, Одинцовский район, 143080 пос. ВНИИССОК, Селекционная 14</p></bio><bio xml:lang="en"><p>Doctor of Agricultural Sciences, leading researcher, </p><p>Moscow region</p></bio><email xlink:type="simple">segolubkina@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Синдирева</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sindireva</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор биологических наук, профессор,</p><p>г. Омск</p></bio><bio xml:lang="en"><p>Doctor of Biological Sciences, Professor, </p><p>Omsk</p></bio><email xlink:type="simple">sindireva72@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зайцев</surname><given-names>В. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Zaitsev</surname><given-names>V. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор сельскохозяйственных наук, Заслуженный деятель науки, профессор,</p><p>г. Астрахань</p></bio><bio xml:lang="en"><p>Doctor of Agricultural Sciences, Honored Scientist of Russia, Professor, </p><p>Astrakhan</p></bio><email xlink:type="simple">viacheslav-zaitsev@yandex.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Агрохимический испытательный центр Всероссийский научно-исследовательский институт селекции и семеноводства овощных культур<country>Россия</country></aff><aff xml:lang="en">Agrochemical research center, All-Russian Research Institute of Vegetable breeding and-Seeds production<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">Омский государственный аграрный университет<country>Россия</country></aff><aff xml:lang="en">Omsk State Agrarian University<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru">Астраханский государственный технический университет,<country>Россия</country></aff><aff xml:lang="en">Astrakhan State Technical University<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>01</day><month>04</month><year>2017</year></pub-date><volume>12</volume><issue>1</issue><fpage>107</fpage><lpage>127</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Голубкина Н.А., Синдирева А.В., Зайцев В.Ф., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Голубкина Н.А., Синдирева А.В., Зайцев В.Ф.</copyright-holder><copyright-holder xml:lang="en">Golubkina N.A., Sindireva A.V., Zaitsev V.F.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ecodag.elpub.ru/ugro/article/view/907">https://ecodag.elpub.ru/ugro/article/view/907</self-uri><abstract><sec><title>Цель</title><p>Цель. Оценить причины меж- и внутрирегиональной вариабельности селенового статуса населения.</p></sec><sec><title>Обсуждение</title><p>Обсуждение. Эссенциальность селена для организма человека определяют приоритетность оценки селенового статуса территорий в большинстве стран мира. В то же время вопросы внутрирегиональной вариабельности показателей обеспеченности часто недооцениваются. Показано, что среди факторов, определяющих селеновый статус населения, наиболее значимыми являются геохимическая характеристика почвы и антропогенное влияние. Отмечается важность морей и океанов, как источников микроэлемента. Приводятся примеры значительных внутрирегиональных вариаций в селеновом статусе населения и отмечается важность комплексного подхода к выявлению экологических рисков, связанных с неадекватным потреблением селена, учитывающих как распределение микроэлемента в почве, так и уровни биоконцентрирования различными видами растений, концентрации селена в природных водах, продуктах питания и биологических тканях и жидкостях человека. Отмечается сложность разработки мер оптимизации селенового статуса территории с высоким геохимическим разнообразием и значительным антропогенным влиянием.</p></sec><sec><title>Заключение</title><p>Заключение. Высокая внутрирегиональная вариабельность показателей селенового статуса населения определяет необходимость комплексного подхода к выявлению экологических рисков, связанных с недостатком или избытком селена в окружающей среде, как в районах с интенсивным использованием местных продуктов питания, так и в крупных промышленных регионах и городах, а также в условиях отдельных специфических производств. </p></sec></abstract><trans-abstract xml:lang="en"><p>Aim of the present work was evaluation of factors affecting interregional variability of the human selenium status.</p><sec><title>Discussion</title><p>Discussion. Essentiality of selenium to human beings determines the priority of the selenium status evaluation in different regions of the world. At the same time interregional variability of the human selenium status biomarkers are often underestimated. Among factors affecting the human selenium status geochemical characteristic of soils and anthropogenic influence are proved to be the most significant. The importance of seas and oceans are emphasized as important sources of the element. Examples of great interregional variability of the human selenium status are indicated and the importance of complex approach for evaluation of ecological risks connected with inadequate selenium consumption are emphasized. Such an approach should combine the data of selenium distribution in soils, levels of selenium bio concentration by different plants species, selenium content in water, food products and in human biological fluids and tissues. Difficulties in the human selenium status optimization are shown to be typical in regions with significant geochemical variations and intensive anthropogenic loading.</p></sec><sec><title>Conclusions</title><p>Conclusions. High interregional variability of the human selenium status determines the necessity of complex approach in revealing ecological risks connected with selenium deficiency of excess in the environment both in regions with high utilization of local food products and in large industrial regions and towns and also in conditions of separate specific industrial production. </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>селен</kwd><kwd>селеновый статус</kwd><kwd>население</kwd><kwd>внутрирегиональная вариабельность</kwd><kwd>геохимические и антропогенные факторы влияния</kwd></kwd-group><kwd-group xml:lang="en"><kwd>the human selenium status</kwd><kwd>inter regional variability</kwd><kwd>geochemical and anthropogenic factors</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Oldfield J.E. Selenium World Atlas. SeleniumTellurium Development Association N.Y. 1999. 59 p.</mixed-citation><mixed-citation xml:lang="en">Oldfield J.E. Selenium World Atlas. SeleniumTellurium Development Association N.Y. 1999. 59 p.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Голубкина Н.А, Папазян Т.Т. Селен в питании. Растения, животные, человек. Москва: Печатный город, 2006. 254 с.</mixed-citation><mixed-citation xml:lang="en">Golubkina N.A., Papazyan T.T. Selen v pitanii. Rasteniya, zhivotnye, chelovek [Selenium in Nutrition. Plants, animals, human beings]. Moscow, Pechatny Gorod Publ., 2006. 254 p. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Скальный А.В., Киселев М.Ф. Элементный статус населения России. Санкт-Петербург: Медкнига "ЭЛ-БИ-СПб". 2010. 416 c.</mixed-citation><mixed-citation xml:lang="en">Skalny A.V., Kiselev M.F. Elementnyi status naseleniya Rossii [The human selenium status in Russia]. St. Petersburg, Medkniga "ELBI-SPT" Publ., 2010 (In Russian) 416 pp.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Stoffaneller R., Morse N.L. A review of dietary selenium intake and selenium status in Europe and the Middle East. Nutrients. 2015. vol. 7, рр. 1494-1537. DOI: 10.3390/nu7031494</mixed-citation><mixed-citation xml:lang="en">Stoffaneller R., Morse N.L. A review of dietary selenium intake and selenium status in Europe and the Middle East. Nutrients. 2015. vol. 7, рр. 1494-1537. DOI: 10.3390/nu7031494</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Combs G.F. Biomarkers of selenium status. Nutrients. 2015. vol. 7, pp. 2209-2236. DOI: 10.3390/nu7042209</mixed-citation><mixed-citation xml:lang="en">Combs G.F. Biomarkers of selenium status. Nutrients. 2015. vol. 7, pp. 2209-2236. DOI: 3390/nu7042209</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Salbe A.D., Levander O.A. Effect of various dietary factors on the deposition of selenium in the hair and nails of rats. Journal of Nutrition. 1990. vol. 120(2), pp. 200-206.</mixed-citation><mixed-citation xml:lang="en">Salbe A.D., Levander O.A. Effect of various dietary factors on the deposition of selenium in the hair and nails of rats. Journal of Nutrition. 1990. vol. 120(2), pp. 200-206.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Elsom R., Sanderson P., Hesketh J.E., Jackson M.J., Fairweather-Tait S.J., Akesson B., Handy J., Arthur J.R. Functional markers of selenium status: UK Food Standards Agency Workshop report // British Journal of Nutrition. 2006. vol. 96, рp. 980-984.</mixed-citation><mixed-citation xml:lang="en">Elsom R., Sanderson P., Hesketh J.E., Jackson M.J., Fairweather-Tait S.J., Akesson B., Handy J., Arthur J.R. Functional markers of selenium status: UK Food Standards Agency Workshop report. British Journal of Nutrition. 2006. vol. 96, рp. 980-984.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Duffield A.H., Thomson C.D., Hill K.E., Williams An estimation of selenium requirements for New Zealanders // American Journal of Clinical Nutrition. 1999. vol. 70, рр. 896-903.</mixed-citation><mixed-citation xml:lang="en">Duffield A.H., Thomson C.D., Hill K.E., Williams An estimation of selenium requirements for New Zealanders. American Journal of Clinical Nutrition. 1999. vol. 70, рр. 896-903.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Alfthan G., Aro A., Arvilommi H. Selenium metabolism and platelet glutathione peroxidase activity in healthy Finnish men: effects of selenium yeast, selenite and selenite // American Journal of Clinical Nutrition. 1991.vol. 53, pp. 120-125.</mixed-citation><mixed-citation xml:lang="en">Alfthan G., Aro A., Arvilommi H. Selenium metabolism and platelet glutathione peroxidase activity in healthy Finnish men: effects of selenium yeast, selenite and selenite. American Journal of Clinical Nutrition. 1991.vol. 53, pp. 120-125.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Ермаков В.В. Биогеохимия селена и его значение в профилактике эндемических заболеваний человека // Вестник отделения наук о земле РАН. 2004. Т. 22, N1. С. 1-17.</mixed-citation><mixed-citation xml:lang="en">Ermakov V.V. Biogeochemistry of selenium and its significance in prophylactics of endemic human diseases. Vestnik otdeleniya nauk o zemle RAN [Vestnik of Earth science RAS]. 2004. Vol. 22, no. 1, pp. 1-17. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Скальный А.В., Сальникова Е.В., Кудрявцева Е.А., Кустова А.С. Аккумуляция тяжелых металлов и микроэлементов в волосах населения Оренбургской области // Микроэлементы в медицине. 2012. Т. 13, вып. 4. С. 42-45.</mixed-citation><mixed-citation xml:lang="en">Skalny A.V., Salnikova E.V., Kudriavtseva E.A., Kustova A.S. Accumulation of heavy metals and trace elements in hair of Orenburg population. Mikroelementy v meditsine [Trace Elements in Medicine]. 2012. Vol. 13, no. 4. pp. 42-45. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Свечникова А.А., Голубкина Н.А., Мелякина Э.И. Обеспеченность селеном жителей Астраханской области // Вопросы питания. 2010. Т. 79, N 2. С. 78-80.</mixed-citation><mixed-citation xml:lang="en">Svechnikova A.A., Golubkina N.A., Meliakina E.I. The human selenium status of Astrakhan region. Voprosy pitaniya [Voprosy pinanya]. 2010. Vol. 79, no. 2, pp. 78-80. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Голубкина Н.А., Синдирева А.В., Зайко О.А., Алфтан Г. Селеновый статус Омской области // Сибирский экологический журнал. 2012. N 3. С. 389-396.</mixed-citation><mixed-citation xml:lang="en">Golubkina N.A., Sindireva А.V., Zaiko О.А., Alfthan G. Selenium status of Omsk region. Sibirskii ekologicheskii zhurnal [Siberian ecological journal]. 2012. no. 3, pp. 389-396. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Синдирева А.В., Голубкина Н.А., Зайко О.А. Селеновый статус населения Омской области // Медицинская наука и образование Урала. 2009. N 2. С. 66-69.</mixed-citation><mixed-citation xml:lang="en">Sindireva A.V., Golubkina N.А., Zaiko О.А.The human selenium status in Omsk region. Meditsinskaya nauka i obrazovanie Urala [Medical science and education of the Ural]. 2009. no. 2, pp. 66-69. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Синдирева А.В., Голубкина Н.А. Оценка селенового статуса территории Омской области // Омский научный вестник. 2011. N1 (104). С. 192-196.</mixed-citation><mixed-citation xml:lang="en">Sindireva A.V., Golubkina N.A. Evaluation of selenium status of the territory of Omsk region. Omskii nauchnyi vestnik [Omsk Scientific Bulletin]. 2011. no. 1 (104), pp. 192-196. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Александровская Е.Ю., Синдирева А.В., Голубкина Н.А., Чуянова Г.И., Серебренникова А.А. Влияние селена на урожайность и показатели качества зерна яровой мягкой пшеницы в условиях южной лесостепи Омской области // Вестник Омского государственного аграрного университета. 2016. N 1 (21). С. 98−104.</mixed-citation><mixed-citation xml:lang="en">Alexandrovskaya E.Yu., Sindirevaа А.V., Golubkina N.A., Chuyanova G.I., Serebrennikova А.А. Effect of selenium on yield of soft spring wheat and indicators of grain quality in the southern forest-steppe conditions of the Omsk region. Vestnik Omskogo gosudarstvennogo agrarnogo universiteta [Bulletin of the Omsk State Agrarian University]. 2016. no. 1 (21), pp. 98−104. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Golubkina N.A., Alfthan G. The human selenium status in 27 regions of Russia. Journal of Trace Elements in Medicine and Biology. 1999. vol. 13, iss. 1-2, рр. 15-20. DOI:10.1016/S0946-672X(99)80018-2</mixed-citation><mixed-citation xml:lang="en">Golubkina N.A., Alfthan G. The human selenium status in 27 regions of Russia. Journal of Trace Elements in Medicine and Biology. 1999. vol. 13, iss. 1-2, рр. 15-20. DOI:10.1016/S0946-672X(99)80018-2</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Сенькевич О.А., Голубкина Н.А., Ковальский Ю.Г., Сиротина З.В., Искренок Г.В., Бельды Д.С. Обеспеченность селеном жителей Хабаровского края // Дальневосточный медицинский журнал. 2009. N 1. С. 82-84.</mixed-citation><mixed-citation xml:lang="en">Senkevich O.A., Golubkina N.А., Kovalsky Yu.G., Sirotina Z.V., Iskrenok G.V., Beldy D.S. The human selenium status in Khabarovsk land. Dal'nevostochnyi meditsinskii zhurnal [Far- Eastern medical journal]. 2009. no. 1, pp. 82-84. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Yang G., Wang S., Zhou R., Sun S. Endemic selenium intoxication of humans in China // American Journal of Clinical Nutrition. 1983. vol. 37, pp. 872-881.</mixed-citation><mixed-citation xml:lang="en">Yang G., Wang S., Zhou R., Sun S. Endemic selenium intoxication of humans in China. American Journal of Clinical Nutrition. 1983. vol. 37, pp. 872-881.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Коробова Е.М., Березкин В.Ю., Данилова В.Н., Хушвахтова С.Д. Оценка содержания селена в водах питьевого назначения, почвах и укосах пастбищных трав Брянской области // Материалы VII Биогеохимической школы «Фундаментальные и инновационные аспекты биогеохимии, Москва, 2011. С. 54-57.</mixed-citation><mixed-citation xml:lang="en">Korobova E.M., Berezkin V.Yu., Danilova V.N., Khushvakhtova S.D. Otsenka soderzhaniya selena v vodakh pit'evogo naznacheniya, pochvakh i ukosakh pastbishchnykh trav Bryanskoi oblasti [Evaluation of selenium contet in drinking water, soil and fodder plants in Briansk region]. Materialy VII Biogeokhimicheskoi shkoly «Fundamental'nye i innovatsionnye aspekty biogeokhimii,  Moskva, 2011 [Proceedings of the VII biogeochemical school «Fundamental and innovational aspects of biogeochemistry, Moscow, 2011]. Moscow, 2011, pp. 54-57 (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Ермаков В.В., Воронцова О.В. Биогеохимия селена в почвах // Материалы VI-XII биогеохимических чтения памяти В.В. Ковальского. М.-ГЕОХИ. 2010. С.268-287.</mixed-citation><mixed-citation xml:lang="en">Ermakov V.V., Vorontsova O.V. Biogeokhimiya selena v pochvakh [Biogeochemistry of selenium in soils]. Materialy VI-XII biogeokhimicheskikh chteniya pamyati V.V. Koval'skogo, Moskva, 2010 [Proceedings of the VI-XII VV Kovalsky Biogeochemical readings, Мoscow, 2010]. Moscow, Institute of geochemistry and analytical chemistry Publ., 2010, pp. 268-287. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Fordyce F.M. Selenium deficiency and toxicity in the environment. Essentials of Medical Geology. 2012, рр. 375-416. DOI 10.1007/978-94-007-4375-5_16</mixed-citation><mixed-citation xml:lang="en">Fordyce F.M. Selenium deficiency and toxicity in the environment. Essentials of Medical Geology. 2012, рр. 375-416. DOI 10.1007/978-94-007-4375-5_16</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Fordyce F.M. Zhang G., Green K., Liu X. Soil, grain and water chemistry and human selenium imbalance in Enshi District, Hubei province, China // Applied Geochemistry. 2000. vol. 15, iss. 1, pp. 117-132.</mixed-citation><mixed-citation xml:lang="en">Fordyce F.M. Zhang G., Green K., Liu X. Soil, grain and water chemistry and human selenium imbalance in Enshi District, Hubei province, China. Applied Geochemistry. 2000. vol. 15, iss. 1, pp. 117-132.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Neal R.H. Selenium in Heavy metals in soils (DJ Alloway ed) Blackie Academic and Professional, London. 1995, pp. 260-283.</mixed-citation><mixed-citation xml:lang="en">Neal R.H. Selenium in Heavy metals in soils (DJ Alloway ed) Blackie Academic and Professional, London. 1995, pp. 260-283.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Aspila P. The history of selenium supplemented fertilization in Finland // Proc.Twenty years of selenium fertilization. 2005. 8-9 Sept., Helsinki, ed. M. Eurola, pp. 8-13.</mixed-citation><mixed-citation xml:lang="en">Aspila P. The history of selenium supplemented fertilization in Finland. Proc.Twenty years of selenium fertilization. 2005. 8-9 Sept., Helsinki, ed. M. Eurola, pp. 8-13.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Бурцева Т.И., Голубкина Н.А., Мирошников С.А., Скальный А.В. Содержание селена в мясе животных и птицы, произведенных на территории Оренбургской области // Вопросы питания. 1998. Т.8. С. 2-5.</mixed-citation><mixed-citation xml:lang="en">Burtseva T.I., Golubkina N.A., Miroshnikov S.A., Salny A.V. Selenium content in poultry and meat of domestic animals of Orenburg region. Voprosy pitanya [Problems of nutrition]. 1998. vol. 8, pp. 2-5. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Бурцева Т.И., Голубкина Н.А., Мирошников С.А. Содержание селена в хлебе Оренбургской области // Вопросы питания. 2009. Т.78, N4. С. 47-50.</mixed-citation><mixed-citation xml:lang="en">Burtseva T.I., Golubkina N.A., Miroshnikov S.A. Selenium content in bread of Orenburg region. Voprosy pitanya [Problems of nutrition]. 2009. vol. 78, no. 4, pp. 47-50. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Tan J. (ed), The atlas of endemic diseases and their environments in the people’s republic of China. Science Press, Beijing 1989. 193 p.</mixed-citation><mixed-citation xml:lang="en">Tan J. (ed), The atlas of endemic diseases and their environments in the people’s republic of China. Science Press, Beijing 1989. 193 p.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Aro A., Kumpulainen J. Factors affecting the selenium intake of people in Transbaikalian Russia // Biology and Trace Elements Research. 1994. vol. 40, pp. 277-285.</mixed-citation><mixed-citation xml:lang="en">Aro A., Kumpulainen J. Factors affecting the selenium intake of people in Transbaikalian Russia. Biology and Trace Elements Research. 1994. vol. 40, pp. 277-285.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Davies E.B., Watkinson J.H. Uptake of native and applied selenium by pasture species // New Zealand Agricultural Research. 1966. vol. 9, pp. 317-324.</mixed-citation><mixed-citation xml:lang="en">Davies E.B., Watkinson J.H. Uptake of native and applied selenium by pasture species. New Zealand Agricultural Research. 1966. vol. 9, pp. 317-324.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Banuelos G.S., Meek D.W. Accumulation of selenium in plants grown on selenium-treated soil // Journal of Environmental Quality. 1990. vol. 19, pp. 772-777. doi:10.2134/jeq1990.00472425001900040023x</mixed-citation><mixed-citation xml:lang="en">Banuelos G.S., Meek D.W. Accumulation of selenium in plants grown on selenium-treated soil. Journal of Environmental Quality. 1990. vol. 19, pp. 772-777. doi:10.2134/jeq1990.00472425001900040023x</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Guo-Xin Sun, Meharg A.A., Li G., Chen Z., Yang L., Chen S-C., Zhu Y-G. [Distribution of soil selenium in China is potentially controlled by deposition and volatilization?]. Scientific reports, 2016. no. 6, Article number 20953. DOI 10.1038/scep20953 Available at: www.nature.com/scientificreports/). (accessed 10.09.2016)</mixed-citation><mixed-citation xml:lang="en">Guo-Xin Sun, Meharg A.A., Li G., Chen Z., Yang L., Chen S-C., Zhu Y-G. [Distribution of soil selenium in China is potentially controlled by deposition and volatilization?]. Scientific reports, 2016. no. 6, Article number 20953. DOI 10.1038/scep20953 Available at: www.nature.com/scientificreports/). (accessed 10.09.2016)</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Nriagu J.O. Occurrence and distribution of selenium, CRC Press. Boca Raton, FL, 1989. 214 p.</mixed-citation><mixed-citation xml:lang="en">Nriagu J.O. Occurrence and distribution of selenium, CRC Press. Boca Raton, FL, 1989. 214 p.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Голубкина Н.А. Селеновый статус Калининградской области // Микроэлементы в медицине. 2016. N4. C. 43-45.</mixed-citation><mixed-citation xml:lang="en">Golubkina N.A. Selenium status of Kaliningrad region. Mikroelementy v meditsine [Trace Elements in Medicine]. 2016. no. 4, pp. 43-45. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Haygarth P.M. Global importance and cycling of selenium // Selenium in the environment (WT Frabkenberger, S Benson eds)-Marcel-Dekker, New York. 1994, pp. 1-28.</mixed-citation><mixed-citation xml:lang="en">Haygarth P.M. Global importance and cycling of selenium. Selenium in the environment (WT Frabkenberger, S Benson eds)-Marcel-Dekker, New York. 1994, pp. 1-28.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Голубкина Н.А., Бурцева Т.И., Гаценко А.Ю. Показатели качества питьевой воды Оренбургской области // Гигиена и санитария. 2011. N 1. С. 70-74.</mixed-citation><mixed-citation xml:lang="en">Golubkina N.A., Burtseva T.I., Gatsenko A.Yu. Water quality parameters in Orenburg region. Gigiena i Sanitariia [Hygiene and sanitary]. 2011. no. 1, pp. 70-74. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Быстрых И.И., Перепелкин С.В., Кузьмин С.А., Тиньков А.Н., Осиян С.А. Биоэлементы в почвах Оренбуржья // Вестник ОГУ. 2004. N4. С. 19-20.</mixed-citation><mixed-citation xml:lang="en">Bistrikh I.I., Perepelkin S.V., Kuzmin S.А., Tinkov A.N., Osian S.А. Microelements in soils of Orenburg region. Vestnik of OGU [Vestnik of OSU]. 2004. no. 4, pp. 19-20. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Голубкина Н.А., Хотимченко С.А. Селен в продуктах питания Уральского экономического района // Гигиена и санитария. 1994. Т.7. С.12-14.</mixed-citation><mixed-citation xml:lang="en">Golubkina N.A., Khotimchenko S.A. Selenium in food products of the Ural economical region. Gigiena i Sanitariia [Hygiene and sanitary].1994. vol. 7, pp. 12-14. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Голубкина Н.А. Потребление селена жителями Брянской области в районах радиоактивного заражения // Вопросы питания. 1994. N4. С. 3-5.</mixed-citation><mixed-citation xml:lang="en">Golubkina N.A. Selenium consumption by residents of Briansk region in regions of nuclea contamination. Voprosy pitanya [Problems of nutrition]. 1994. no. 4, pp. 3-5. (In Russian)</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
