<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ecodag</journal-id><journal-title-group><journal-title xml:lang="ru">Юг России: экология, развитие</journal-title><trans-title-group xml:lang="en"><trans-title>South of Russia: ecology, development</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1992-1098</issn><issn pub-type="epub">2413-0958</issn><publisher><publisher-name>State Institute of Applied Ecology of the Republic of Dagestan</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18470/1992-1098-2024-3-10</article-id><article-id custom-type="elpub" pub-id-type="custom">ecodag-3227</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЭКОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ECOLOGY</subject></subj-group></article-categories><title-group><article-title>Экологические аспекты изучения тиреоидной функции щитовидной железы у женщин репродуктивного возраста, проживающих в регионе с дефицитом йода (на примере Ахтынского района Республики Дагестан)</article-title><trans-title-group xml:lang="en"><trans-title>Ecological aspects of studying the thyroid function of the thyroid gland in women of reproductive age living in a region with iodine deficiency (Akhtynsky district, Republic of Dagestan, Russia)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8273-0944</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Джалилова</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Dzhalilova</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Альбина Н. Джалилова, кандидат медицинских наук, доцент кафедры акушерства и гинекологии</p><p>367000 , г. Махачкала, ул. Ленина, 1. Тел. +79286754517 </p></bio><bio xml:lang="en"><p>Albina N. Dzhalilova, Ph.D. Medical Sciences, Associate Professor, Department of Obstetrics and Gynecology</p><p>1 Lenina St, Makhachkala, 367000. Tel. +79286754517 </p></bio><email xlink:type="simple">albinanur102@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4034-0742</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Омарова</surname><given-names>С. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Omarova</surname><given-names>S. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Салидат М. Омарова </p><p>Махачкала </p></bio><bio xml:lang="en"><p>Salidat M. Omarova </p><p>Makhachkala </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4754-6794</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Джалилова</surname><given-names>Д. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Dzhalilova</surname><given-names>D. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Динара Н. Джалилова </p><p>Махачкала </p></bio><bio xml:lang="en"><p>Dinara N. Dzhalilova </p><p>Makhachkala </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0700-2378</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Царуева</surname><given-names>Т. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Tsarueva</surname><given-names>T. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тамара В. Царуева </p><p>Махачкала </p></bio><bio xml:lang="en"><p>Tamara V. Tsarueva </p><p>Makhachkala </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6550-9348</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Абудуев</surname><given-names>Н. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Abuduev</surname><given-names>N. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Назирбек К. Абудуев </p><p>Махачкала </p></bio><bio xml:lang="en"><p>Nazirbek K. Abuduev </p><p>Makhachkala </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8229-5935</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Газиев</surname><given-names>Г. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Gaziev</surname><given-names>G. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гази М. Газиев </p><p>Махачкала </p></bio><bio xml:lang="en"><p>Gazi M. Gaziev </p><p>Makhachkala </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4635-6796</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Юсупова</surname><given-names>М. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Yusupova</surname><given-names>M. T.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Малькура Т. Юсупова </p><p>Махачкала </p></bio><bio xml:lang="en"><p>Malkura T. Yusupova </p><p>Makhachkala </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0236-891X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Саидова</surname><given-names>П. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Saidova</surname><given-names>P. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Патимат С. Саидова </p><p>Махачкала </p></bio><bio xml:lang="en"><p>Patimat S. Saidova </p><p>Makhachkala </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4939-2637</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Магомедова</surname><given-names>У. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Magomedova</surname><given-names>U. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Умият А. Магомедова </p><p>Махачкала </p></bio><bio xml:lang="en"><p>Umiyat A. Magomedova </p><p>Makhachkala </p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Дагестанский государственный медицинский университет Минздрава Российской Федерации<country>Россия</country></aff><aff xml:lang="en">Dagestan State Medical University, Ministry of Health of the Russian Federation<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>21</day><month>10</month><year>2024</year></pub-date><volume>19</volume><issue>3</issue><fpage>110</fpage><lpage>115</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Джалилова А.Н., Омарова С.М., Джалилова Д.Н., Царуева Т.В., Абудуев Н.К., Газиев Г.М., Юсупова М.Т., Саидова П.С., Магомедова У.А., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Джалилова А.Н., Омарова С.М., Джалилова Д.Н., Царуева Т.В., Абудуев Н.К., Газиев Г.М., Юсупова М.Т., Саидова П.С., Магомедова У.А.</copyright-holder><copyright-holder xml:lang="en">Dzhalilova A.N., Omarova S.M., Dzhalilova D.N., Tsarueva T.V., Abuduev N.K., Gaziev G.M., Yusupova M.T., Saidova P.S., Magomedova U.A.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ecodag.elpub.ru/ugro/article/view/3227">https://ecodag.elpub.ru/ugro/article/view/3227</self-uri><abstract><p>Цель: представить эпидемиологические аспекты изучения тиреоидной функции щитовидной железы.</p><p>В статье представлены результаты клинико‐лабораторного обследо‐ вания и эпидемиологические аспекты изучения тиреоидной функции щитовидной железы у 120 женщин репродуктивного возраста, проживающих на территории с дефицитом йода (территория Ахтынского района Республики Дагестан, расположенный на высоте 1675 метров над уровнем моря). Женщины обследованы на заболевания щитовидной железы и на наличие внутриутробных инфекций: TORCH‐токсоплазмоз, орнитоз, краснуха, цитомегало‐ и герпесвирусы.</p><p>У всех обследованных установлены заболевания щитовидной железы (женщины состоят на учете у эндокринолога в Эндокринологическом диспансере). Всем женщинам проведена коррекция йододефицита в виде йодной профилактики путём приёма препаратов, содержащих суточную потребность в йоде до 250 мкг для нормализации функции щитовидной железы.</p><p>Внутриутробные инфекции (ВУИ) обнаружены у 76 женщин, что составляет 69 %. Также проведена терапия внутриутробных инфекций женщин, состоящих на учёте в женской консультации районной больницы.</p></abstract><trans-abstract xml:lang="en"><p>Aim. To present epidemiological aspects of the study of thyroid function of the thyroid gland.The article presents the results of a clinical and laboratory examination and epidemiological aspects of studying the thyroid function of the thyroid gland in 120 women of reproductive age living in an area with iodine deficiency (Akhtynsky district, Republic of Dagestan – located at an altitude of 1.675 metres above sea level). The women were examined for thyroid diseases and for the presence of intrauterine infections: TORCH toxoplasmosis, ornithosis, rubella, cytomegalo‐ and herpesviruses.All the examined patients had thyroid diseases (the women are registered with an endocrinologist at an Endocrinological Dispensary). All women underwent correction of iodine deficiency in the form of iodine prophylaxis by taking medications containing a daily iodine requirement of up to 250 mcg to normalize thyroid function.Intrauterine infections (IUI) were found in 76 women (69 %. of the patients examined). Intrauterine infections of women registered in the women's clinic of the district hospital were also treated.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>Фертильный возраст</kwd><kwd>щитовидная железа</kwd><kwd>йододефицит</kwd><kwd>внутриутробная патология</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Fertile age</kwd><kwd>thyroid gland</kwd><kwd>iodine deficiency</kwd><kwd>intrauterine pathology</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Петунина Н.А., Тельнова М.Э. Йододефицитные заболевания: современный подход к профилактике // Гинекология. 2016. Т. 18. N 4. С. 45–48.</mixed-citation><mixed-citation xml:lang="en">Petunina N.A., Telnova M.E. Iodine deficiency diseases: a modern approach to prevention. Ginekologiya [Gynecology]. 2016, vol. 18, no. 4, pp. 45–48. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Cheserek M.J., Wu G., Shen L. et al. Evaluation of the relationship between subclinical hypothyroidism and metabolic syndrome components among workers // Int. J. Occup. Med. Environ. Health. 2014. V. 27. N 2. P. 175–187. https://doi.org/10.2478/s13382‐014‐0240‐5</mixed-citation><mixed-citation xml:lang="en">Cheserek M.J., Wu G., Shen L. et al. Evaluation of the relationship between subclinical hypothyroidism and metabolic syndrome components among workers. Int. J. Occup. Med. Environ. Health, 2014, vol. 27, no. 2, pp. 175–187. https://doi.org/10.2478/s13382‐014‐0240‐5</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Radetti G., Grugni G., Lupi F., et al. The relationship between hyperthyrotropinemia and metabolic and cardiovascular risk fac‐tors in a large group of overweight and obese children and adolescents // J Endocrinol Invest. 2017. V. 40. N 12. P. 1311–1319. https://doi.org/10.1007/s40618‐017‐0705‐z</mixed-citation><mixed-citation xml:lang="en">Radetti G., Grugni G., Lupi F., et al. The relationship between hyperthyrotropinemia and metabolic and cardiovascular risk fac‐tors in a large group of overweight and obese children and adolescents. J Endocrinol Invest, 2017, vol. 40, pp. 1311–1319. https://doi.org/10.1007/s40618‐017‐0705‐z</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Sert A., Pirgon O., Aypar E., Yilmaz H. et al. Subclinical hypothyroidism as a risk factor for the development of cardiovascular disease in obese ado‐lescents with nonalcoholic fatty liver disease // Pediatric Cardiology. 2013. V. 34. N 5. P. 1166–1174.</mixed-citation><mixed-citation xml:lang="en">Sert A., Pirgon O., Aypar E., Yilmaz H. et al. Subclinical hypothyroidism as a risk factor for the development of cardiovascular disease in obese ado‐lescents with nonalcoholic fatty liver disease. Pediatric Cardiology. 2013, vol. 34, no. 5, pp. 1166–1174.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Kulaga Z., Litwin M., Tkaczyk M. et al. The height‐, weight‐, and BMI‐for‐age of Polish school‐aged children and adolescents relative to international and local growth references // BMC Public Health. 2010. N 10. Article ID: 109. https://doi.org/10.1186/1471‐2458‐10‐109</mixed-citation><mixed-citation xml:lang="en">Kulaga Z., Litwin M., Tkaczyk M. et al. The height‐, weight‐, and BMI‐for‐age of Polish school‐aged children and adolescents relative to international and local growth references. BMC Public Health, 2010, no. 10, article id: 109. https://doi.org/10.1186/1471‐2458‐10‐109</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">De Benoist B., McLean E., Andersson M., Rogers L. Iodine deficiency in 2007: global progress since 2003 // Food Nutr. Bull. 2008. V. 29. N 3. P. 195–202. https://doi.org/10.1177/156482650802900305</mixed-citation><mixed-citation xml:lang="en">De Benoist B., McLean E., Andersson M., Rogers L. Iodine deficiency in 2007: global progress since 2003. Food Nutr. Bull., 2008, vol. 29, no. 3, pp. 195–202. https://doi.org/10.1177/156482650802900305</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Яхияев М.А., Салихов Ш.К., Атаев М.Г. и др. Эндемический зоб – следствие дефицита йода и селена в природной среде // Экологическая медицина. 2019. Т. 1. С. 66–71.</mixed-citation><mixed-citation xml:lang="en">Yakhyaev M.A., Salikhov Sh.K., Ataev M.G. et al. Endemic goiter is a consequence of iodine and selenium deficiency in the natural environment. Ekologicheskaya meditsina [Environmental medicine]. 2019, vol. 1, pp. 66–71. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Мельниченко Г.А., Трошина Е.А., Платонова Н.М., Панфилова Е.А., Рыбакова А.А., Абдулхабирова Ф.М., Бостановаи Ф.А. Йододефицитные заболевания щитовидной железы в Российской Федерации: современное состояние проблемы. Аналитический обзор публикаций и данных официальной государственной статистики (Росстат) // Consilium Medicum. 2019.Т. 21. N 4. С. 14–20. https://doi.org/10.26442/20751753.2019.4.190337</mixed-citation><mixed-citation xml:lang="en">Melnichenko G.A., Troshina E.A., Platonova N.M., Panfilova E.A., Rybakova A.A., Abdulkhabirova F.M., Bostanova F.A. Iodine deficiency thyroid disease in the Russian Federation: the current state of the problem. Аnalytical review of publications and data of official state statistics (Rosstat). Consilium Medicum, 2019, vol. 21, no. 4, pp. 14–20. (In Russian) https://doi.org/10.26442/20751753.2019.4.190337</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Трошина Е.А. Устранение дефицита йода – забота о здоровье нации. Экскурс в историю, научные аспекты и современное состояние правового регулирования проблемы в России // Проблемы эндокринологии. 2022. Т. 68. N 4. С. 4–12. https://doi.org/10.14341/probl13154</mixed-citation><mixed-citation xml:lang="en">Troshina E.A. Elimination of iodine deficiency is a concern for the health of the nation. An excursion into the history, scientific aspects and the current state of the legal regulation of the problem in Russia. Problems of Endocrinology, 2022, vol. 68, no. 4, pp. 4–12. (In Russian) https://doi.org/10.14341/probl13154</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Петунина Н.А., Трухина Л.В. Болезни щитовидной железы. Москва: Издательская группа «ГЭОТАР‐Медиа», 2011. 216 с.</mixed-citation><mixed-citation xml:lang="en">Petunina N.A., Trukhina L.V. Bolezni shchitovidnoi zhelezy [Diseases of the thyroid gland]. Moscow, GeoTAr‐media Publ., 2011, 216 p. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Раджабова Ш.Ш., Царуева Т.В., Джалилова А.Н., Джалилова Д.Н. К вопросу о тиреоидной функции щитовидной железы беременных, проживающих в йододефицитном районе (Республика Дагестан, Ахтынский район, 1675 м над уровнем моря) // Клинический разбор в общей медицине. 2024. Т. 5. N 3. С. 88–92. https://doi.org/10.47407/kr2023.5.3.00377</mixed-citation><mixed-citation xml:lang="en">Radzhabova Sh.Sh., DzhalilovaA.n., Tsarueva T.V., Dzhalilova D.N. To the question of the thyroid function of the thyroid gland of pregnant women living in iodine‐deficiency region (Republic of Dagestan, Akhtyn district, 1675 meters above sea level). Clinical review for general practice, 2024, vol. 5, no. 3, pp. 88–92. (In Russian) https://doi.org/10.47407/kr2023.5.3.00377</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
